SCHEMBL30748904

SCHEMBL30748904

CC1(C)C(=O)N(c2ccc(N3CCOCC3)c(F)c2)c2nc(Cl)nc(Cl)c21

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAD51 Q06609 3/20 0.42
MTOR P42345 1/20 0.40
MAOB P27338 6/20 0.40
LMNA P02545 2/20 0.39
MAOA P21397 2/20 0.39
PTGS1 P23219 1/20 0.39
CALML3 P27482 1/20 0.39
SDHA P31040 1/20 0.39
KDM1A O60341 1/20 0.39
PDE3B Q13370 4/20 0.38
PDE3A Q14432 4/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.38
F10 P00742 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748931 0.84 PDE3B (0.41) PDE3BPDE3AALDH1A1SMN1; SMN2NPC1
SCHEMBL30748750 0.84 MTOR (0.36) RAD51MTORMAOBLMNAMAOA
SCHEMBL30749097 0.80 MAPT (0.44) ALDH1A1HPGDSMN1; SMN2
SCHEMBL30749139 0.76 MAOB (0.41) MAOBLMNAMAOAPTGS1CALML3
SCHEMBL30748801 0.72 ELANE (0.37) ALDH1A1SMN1; SMN2NPC1
SCHEMBL30749100 0.72 PRKDC (0.42) RAD51ALDH1A1SMN1; SMN2
SCHEMBL30749140 0.71 MAPT (0.39) RAD51LMNAALDH1A1SMN1; SMN2
SCHEMBL30749007 0.71 ELANE (0.44) ALDH1A1
SCHEMBL30748903 0.68 ALOX15 (0.35)
SCHEMBL30748982 0.68 PGR (0.37) RAD51ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT RAD51 2049/4885MTOR 1201/4885MAOB 857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.