SCHEMBL30749140

SCHEMBL30749140

O=C1N(c2ccc(N3CCOCC3)cc2)c2nc(Cl)nc(Cl)c2C12CCCC2

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
RAD51 Q06609 2/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
PGR P06401 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK1 P28482 1/20 0.36
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
PTGS2 P35354 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
TNKS O95271 1/20 0.35
TNKS2 Q9H2K2 1/20 0.35
CNR2 P34972 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691365 0.81 MAPT (0.33) MAPTL3MBTL1RAD51ALDH1A1
SCHEMBL31691437 0.80 MAPT (0.32) MAPTL3MBTL1RAD51PGRALDH1A1
SCHEMBL30748982 0.78 PGR (0.37) RAD51MEN1KMT2APGRALDH1A1
SCHEMBL30748928 0.76 MAPT (0.34) MAPTL3MBTL1MEN1KMT2AKDM4E
SCHEMBL30749044 0.76 ALDH1A1 (0.34) PGRSMN1; SMN2ALDH1A1
SCHEMBL30748944 0.76 CCNE1 (0.39) MAPTL3MBTL1RAD51MEN1KMT2A
SCHEMBL30749110 0.75 MAPT (0.33) MAPTL3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL30749074 0.74 L3MBTL1 (0.35) MAPTL3MBTL1LMNA
SCHEMBL31626913 0.73 ALOX5AP (0.36) PGR
SCHEMBL30748855 0.73 SYK (0.39) MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT MAPT 3029/4885L3MBTL1 517/4885RAD51 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.