SCHEMBL30749136

SCHEMBL30749136

CC1(C)C(=O)N(c2cnc(N3CCC(F)(F)C3)nc2)c2nc(Cl)nc(Cl)c21

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACACB O00763 6/20 0.37
CNR2 P34972 6/20 0.36
DPP4 P27487 2/20 0.34
PDE10A Q9Y233 1/20 0.32
CNR1 P21554 2/20 0.31
ADRA1A P35348 1/20 0.31
OPRM1 P35372 1/20 0.31
OPRL1 P41146 1/20 0.31
MAP3K12 Q12852 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691238 0.82 ACACB (0.34) ACACBCNR2PDE10ACNR1
SCHEMBL30749146 0.82 ADRA1A (0.35) ACACBCNR2ADRA1A
SCHEMBL31691210 0.78 MAPK14 (0.35)
SCHEMBL30748745 0.77 ACACB (0.35) ACACBCNR2DPP4PDE10A
SCHEMBL30749150 0.74 SYK (0.41) ACACBCNR2PDE10AADRA1A
SCHEMBL31691369 0.72 ACACB (0.33) ACACBCNR2
SCHEMBL30749044 0.72 ALDH1A1 (0.34) OPRM1OPRL1
SCHEMBL30748990 0.69 MEN1 (0.31)
SCHEMBL30748805 0.67 KMT2A (0.39) ADRA1A
SCHEMBL30749007 0.67 ELANE (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT ACACB 1127/4885CNR2 2267/4885DPP4 914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.