SCHEMBL307496

SCHEMBL307496

S=C(SCc1ccccc1)n1cccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
IDO1 P14902 9/20 0.47
NOS3 P29474 1/20 0.47
NOS1 P29475 1/20 0.47
NOS2 P35228 1/20 0.47
FBP1 P09467 1/20 0.45
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
HDAC3 O15379 1/20 0.39
HDAC4 P56524 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC7 Q8WUI4 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC10 Q969S8 1/20 0.39
HDAC11 Q96DB2 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14130475 0.92 FBP1 (0.48) CA12CA1CA2CA9IDO1
SCHEMBL22625806 0.80 TAAR1 (0.54) IDO1FBP1TDP1TAAR1L3MBTL1
SCHEMBL165635 0.80 CA12 (0.45) CA12CA1CA2CA9IDO1
SCHEMBL25203952 0.79 IDO1 (0.36) CA12CA1CA2CA9IDO1
SCHEMBL19468360 0.77 MGLL (0.59) CA12CA1CA2CA9IDO1
SCHEMBL161188 0.74 CA12 (0.65) CA12CA1CA2CA9IDO1
SCHEMBL3461371 0.74 CA12 (0.65) CA12CA1CA2CA9IDO1
SCHEMBL30064872 0.74 PKM (0.59) CA12CA1CA2CA9FBP1
SCHEMBL27651206 0.74 FBP1 (0.53) CA12CA1CA2CA9IDO1
Potassium Ion SCHEMBL11493331 0.74 CA12 (0.64) CA12CA1CA2CA9IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 381 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037862-A Degradable bio-based copolymer pressure-sensitive adhesive with high bonding strength and preparation method thereof 吉林大学 2026-05-15 CN claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-11886045-B2 Method for making photochromic contact lenses ALCON INC. (CH) 2024-01-30 US claimed
US-11834383-B2 Energetic feedstock for additive manufacturing LYNNTECH, INC. (US) 2023-12-05 US claimed
WO-2023209570-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-11-02 WO claimed
US-20230339149-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2023-10-26 US claimed
EP-4240578-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES Alcon Inc. (CH) 2023-09-13 EP claimed
US-11708446-B2 Polymers and uses thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-07-25 US claimed
WO-2022097048-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-12 WO claimed
US-20220137433-A1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC. (CH) 2022-05-05 US claimed
EP-3976878-A1 METHODS OF MAKING A DEFLECTION MEMBER The Procter & Gamble Company (US) 2022-04-06 EP claimed
US-20210276931-A1 Energetic Feedstock for Additive Manufacturing LYNNTECH, INC. 2021-09-09 US claimed
US-20210221937-A1 POLYMERS AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-07-22 US claimed
US-11041026-B2 Reactions enabled by thermoresponsive and photoresponsive gels MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2021-06-22 US claimed
US-20200378067-A1 METHODS OF MAKING A DEFLECTION MEMBER THE PROCTER & GAMBLE COMPANY 2020-12-03 US claimed
WO-2020243748-A1 METHODS OF MAKING A DEFLECTION MEMBER THE PROCTER & GAMBLE COMPANY (US) 2020-12-03 WO claimed
WO-2018140977-A1 REACTIONS ENABLED BY THERMORESPONSIVE AND PHOTORESPONSIVE GELS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-08-02 WO claimed
EP-1776399-B1 MONODISPERSE POLYMERS CONTAINING (ALKYL)ACRYLIC ACID MOIETIES, PRECURSORS AND METHODS FOR MAKING THEM AND THEIR APPLICATIONS UNIV GENT (BE) 2012-11-14 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539650-B2 Method for making embedded hydrogel contact lenses INF2, CRYZ, CRYAA CA12 1690/4885CA1 1662/4885CA2 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.