⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31261066 | 0.90 | — | — | |
| SCHEMBL31388158 | 0.81 | AAK1 (0.32) | — | |
| SCHEMBL31261075 | 0.77 | — | — | |
| SCHEMBL31388099 | 0.75 | KMT2A (0.33) | — | |
| SCHEMBL31388133 | 0.73 | — | — | |
| SCHEMBL31388108 | 0.69 | AAK1 (0.32) | — | |
| SCHEMBL31496873 | 0.68 | ALDH1A1 (0.32) | — | |
| SCHEMBL31496970 | 0.67 | LMNA (0.31) | — | |
| SCHEMBL31168642 | 0.66 | PAX8 (0.34) | — | |
| SCHEMBL30752835 | 0.66 | ADORA1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027703-A1 | PRMT5 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2024-02-08 | — | — | WO | disclosed |