Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379121 | 1.00 | TAS2R14 (0.41) | TAS2R14DAODHODHHDAC6ALDH1A1 | |
| SCHEMBL6731917 | 0.80 | DAO (0.43) | DAOHDAC6ALDH1A1HPGDNOTUM | |
| SCHEMBL22208710 | 0.80 | TAS2R14 (0.42) | TAS2R14DAODHODHHDAC6ALDH1A1 | |
| SCHEMBL30755194 | 0.79 | NR1H2 (0.40) | TAS2R14HDAC6NOTUMCFTRCES2 | |
| SCHEMBL24040210 | 0.78 | PDE10A (0.37) | DHODHALDH1A1NOTUMSMN1; SMN2 | |
| SCHEMBL1534127 | 0.76 | CA12 (0.50) | TAS2R14ALDH1A1HPGDLMNAHTT | |
| SCHEMBL14352206 | 0.76 | FABP3 (0.40) | DAONOTUMSMN1; SMN2 | |
| SCHEMBL10598245 | 0.75 | METAP2 (0.41) | DHODHALDH1A1NOTUMLMNASMN1; SMN2 | |
| SCHEMBL6677822 | 0.75 | TAS2R14 (0.44) | TAS2R14DHODHALDH1A1HPGDKMO | |
| SCHEMBL31404957 | 0.73 | KIF11 (0.32) | TAS2R14NOTUMCFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562016-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | Cedilla Therapeutics, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026483-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |