Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Chloromethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloromethane SCHEMBL2233560 | 1.00 | — | — | |
| Ethane SCHEMBL27273578 | 0.89 | — | — | |
| Chloromethane SCHEMBL26697469 | 0.89 | — | — | |
| Chloromethane SCHEMBL15532585 | 0.87 | — | — | |
| Chloromethane SCHEMBL1330521 | 0.87 | — | — | |
| Chloromethane SCHEMBL958 | 0.87 | — | — | |
| Chloromethane SCHEMBL16715719 | 0.87 | — | — | |
| Chloromethane SCHEMBL577900 | 0.87 | — | — | |
| Chloromethane SCHEMBL9950329 | 0.82 | — | — | |
| Water SCHEMBL3838747 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109880453-A | A method of preparing durable non-sticking cooking utensils coating | 浙江乐太新材料有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-108676271-A | A kind of preparation method of medical wear-resistant plastic | 苏州乔纳森新材料科技有限公司 | 2018-10-19 | — | — | CN | claimed |
| CN-108456375-A | Wire and cable protection pipe material and preparation method thereof | 合肥尚强电气科技有限公司 | 2018-08-28 | — | — | CN | claimed |
| CN-103012945-B | A kind of Environment-friendlywallpaper wallpaper and preparation method thereof | Earth guardian (Shouyang) environmental protection new material Co., Ltd. (CN) | 2016-02-10 | — | — | CN | claimed |
| CN-103012945-A | Environment-friendly wallpaper and preparation method thereof | CHAMPION OF THE EARTH SHOUYANG ENVIRONMENTAL PROT NEW MATERIAL CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102348693-A | Methods for preparing JAK inhibitors and related intermediate compounds | INCYTE CORP | 2012-02-08 | — | — | CN | claimed |
| CN-101723941-A | “1,2,4” oxadiazole as a metabotropic glutamate receptor-5 modulator | ASTRAZENECA AB | 2010-06-09 | — | — | CN | claimed |
| CN-1894241-A | \"1, 2, 4\" oxadiazoles as modulators of metabotropic glutamate receptor-5 | ASTRAZENECA AB (SE) | 2007-01-10 | — | — | CN | claimed |
| CN-1169716-A | Alkoximino acetamide | BAYER AG (DE) | 1998-01-07 | — | — | CN | claimed |
| EP-0136518-B1 | PROCESS FOR THE PURIFICATION OF AQUEOUS DISTILLATION RESIDUES OBTAINED DURING THE TREATMENT OF LIQUIDS IN THE PREPARATION OF CELLULOSE ETHERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-09-21 | — | — | EP | claimed |
| US-11820654-B2 | Si-containing film forming precursors and methods of using the same | L'AIR LIQUIDE, SOCIETE ANONYME POUR L'ETUDE ET L'EXPLOITATION DES PROCEDES GEORGES CLAUDE (FR) | 2023-11-21 | — | — | US | disclosed |
| US-20210395890-A1 | SI-CONTAINING FILM FORMING PRECURSORS AND METHODS OF USING THE SAME | AIR LIQUIDE (FR) | 2021-12-23 | — | — | US | disclosed |
| US-11124876-B2 | Si-containing film forming precursors and methods of using the same | L'Air Liquide, Société Anonyme pour l'Etude et l'Exploitation des Procédés Georges Claude (FR) | 2021-09-21 | — | — | US | disclosed |
| EP-3825304-A1 | ANTIBODY-DRUG CONJUGATES AND THE USE OF SAME IN THERAPY | Mc SAF (FR) | 2021-05-26 | — | — | EP | disclosed |
| EP-3521314-B1 | ANTIBODY-DRUG CONJUGATES AND USE THEREOF IN THERAPY | MC SAF (FR) | 2021-02-24 | — | — | EP | disclosed |
| CN-85106733-A | Process for the preparation of novel cephalosporin compounds | — | 1987-01-14 | — | — | CN | disclosed |
| CN-86102923-A | The method for preparing antibiotic derivatives | — | 1986-11-12 | — | — | CN | disclosed |
| US-4515809-A | ANTICHOLESTEROL | ALFA FARMACEUTICI S.P.A. (IT) | 1985-05-07 | — | — | US | disclosed |
| US-4378373-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALFA FARMACEUTICI S.P.A. (IT) | 1983-03-29 | — | — | US | disclosed |
| US-4296125-A | Derivatives of benzoylphenoxyalkanoic acids having normolipemizing activity | ALPHA FARMACEUTICI S.P.A. (IT) | 1981-10-20 | — | — | US | disclosed |