⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5620213 | 0.80 | — | — | |
| SCHEMBL19957426 | 0.78 | — | — | |
| SCHEMBL7135221 | 0.78 | PRMT3 (0.33) | — | |
| SCHEMBL22114486 | 0.78 | ADH1B (0.38) | — | |
| SCHEMBL8189384 | 0.76 | LMNA (0.31) | — | |
| SCHEMBL5449782 | 0.76 | ALDH1A1 (0.43) | — | |
| SCHEMBL19751307 | 0.76 | MVD (0.38) | — | |
| SCHEMBL24738913 | 0.74 | LMNA (0.30) | — | |
| SCHEMBL3402497 | 0.74 | ADH1B (0.40) | — | |
| SCHEMBL24738048 | 0.72 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111732558-B | Method for synthesizing 1-azabicyclo [2,2,1] heptane and derivatives thereof | 南昌大学 | 2021-02-26 | — | — | CN | claimed |
| CN-111732516-B | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2021-01-05 | — | — | CN | claimed |
| CN-111732528-B | Preparation method of N-aryl indoline derivative | 南昌大学 | 2021-01-01 | — | — | CN | claimed |
| CN-111732588-B | Method for synthesizing 5-fluoro-1-azabicyclo [3,2,2] nonane and derivatives thereof | 南昌大学 | 2020-12-08 | — | — | CN | claimed |
| CN-111732528-A | A kind ofNProcess for preparing (E) -arylindoline derivatives | 南昌大学 | 2020-10-02 | — | — | CN | claimed |
| CN-111732516-A | A kind ofNProcess for preparing (E) -aryl-substituted heterocyclic compounds | 南昌大学 | 2020-10-02 | — | — | CN | claimed |
| CN-111732558-A | Method for synthesizing 1-azabicyclo [2,2,1] heptane and derivatives thereof | 南昌大学 | 2020-10-02 | — | — | CN | claimed |
| CN-111732588-A | Method for synthesizing 5-fluoro-1-azabicyclo [3,2,2] nonane and derivatives thereof | 南昌大学 | 2020-10-02 | — | — | CN | claimed |
| CN-117355373-A | Ethylene oligomerization process | 切弗朗菲利浦化学公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-107935909-B | Synthesis method of nintedanib and intermediate thereof | 上海科胜药物研发有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-115135307-A | Carrier for cell delivery | 株式会社ITO | 2022-09-30 | — | — | CN | disclosed |
| CN-111484617-B | Method for improving film performance through crosslinking | 江苏环峰电工材料有限公司 | 2022-08-05 | — | — | CN | disclosed |
| CN-111315729-A | Method for producing 5-hydroxymethylfurfural in the presence of an organic dehydration catalyst and a chloride source | IFP 新能源公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-111295377-A | Method for producing 5-hydroxymethylfurfural in the presence of an inorganic dehydration catalyst and a chloride source | IFP 新能源公司 | 2020-06-16 | — | — | CN | disclosed |
| US-5656604-A | HYPOTENSIVE AGENT; ENDOTHELIN ANTAGONIST | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0706532-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| US-5430022-A | Endothelin antagonists; hypotensive agents; treatment for angina pectoris, brain disorders, asthma, renal failure | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| WO-1995000537-A1 | NEW COMPOUND AND ITS PREPARATION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-01-05 | — | — | WO | disclosed |
| US-5284828-A | Hypotensive agents | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 1994-02-08 | — | — | US | disclosed |
| EP-0457195-A2 | Peptides having endothelin antagonist activity, a process for preparation thereof and pharmaceutical compositions comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-11-21 | — | — | EP | disclosed |