SCHEMBL307644

SCHEMBL307644

CCCCCCCCCCN(CC=O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.41
FABP5 Q01469 3/20 0.38
FABP7 O15540 2/20 0.38
TLR2 O60603 6/20 0.38
EPHX2 P34913 1/20 0.37
EYA2 O00167 1/20 0.36
CASP3 P42574 1/20 0.36
TACR1 P25103 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29883728 1.00 KMT2A (0.41) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL2501976 0.91 KMT2A (0.36) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL2501975 0.91 KMT2A (0.36) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL28416919 0.90 KMT2A (0.40) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL6285017 0.90 KMT2A (0.40) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL307102 0.86 KMT2A (0.42) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL31040664 0.85 KMT2A (0.46) KMT2AFABP5FABP7TLR2CASP3
SCHEMBL21838102 0.85 KMT2A (0.46) KMT2AFABP5FABP7TLR2CASP3
SCHEMBL17108591 0.85 KMT2A (0.44) KMT2AFABP5FABP7TLR2EPHX2
SCHEMBL28414420 0.85 KMT2A (0.46) KMT2AFABP5FABP7TLR2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112592940-B Biological enzyme synthesis method of N- (9-fluorenylmethoxycarbonyl) -decylaminoacetaldehyde 江西邦泰绿色生物合成生态产业园发展有限公司 2023-05-02 CN claimed
CN-107619432-B Glycopeptide derivative and pharmaceutically acceptable salt, preparation method and application thereof 上海来益生物药物研究开发中心有限责任公司 2023-03-17 CN claimed
CN-107629115-B Purification method of telavancin 福建省微生物研究所 2021-05-07 CN claimed
CN-107629116-B Purification method of telavancin 福建省微生物研究所 2021-05-07 CN claimed
CN-111233713-A Synthesis method of telavancin intermediate 福建康鸿生物科技有限公司 2020-06-05 CN claimed
CN-107629115-A A kind of purification process of Te Lawan stars 福建省微生物研究所 2018-01-26 CN claimed
CN-107629116-A A kind of purification process of Te Lawan stars 福建省微生物研究所 2018-01-26 CN claimed
EP-3450450-B1 VANCOMYCIN DERIVATIVE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF SHANGHAI INST MATERIA MEDICA CAS (CN) 2025-08-27 EP disclosed
US-12036219-B2 Methods of treating infections in overweight and obese patients using antibiotics MELINTA SUBSIDIARY CORP. (US) 2024-07-16 US disclosed
US-20240165100-A1 METHODS OF TREATING INFECTIONS IN OVERWEIGHT AND OBESE PATIENTS USING ANTIBIOTICS MELINTA SUBSIDIARY CORP. 2024-05-23 US disclosed
CN-110891590-B Glycopeptide derivative compound and use thereof 英斯麦德公司 2023-07-18 CN disclosed
CN-112592940-B Biological enzyme synthesis method of N- (9-fluorenylmethoxycarbonyl) -decylaminoacetaldehyde 江西邦泰绿色生物合成生态产业园发展有限公司 2023-05-02 CN disclosed
CN-112592940-B Biological enzyme synthesis method of N- (9-fluorenylmethoxycarbonyl) -decylaminoacetaldehyde 江西邦泰绿色生物合成生态产业园发展有限公司 2023-05-02 CN disclosed
US-6444786-B1 BACTERICIDES ADVANCED MEDICINE, INC. 2002-09-03 US disclosed
US-6392012-B1 COMPOUND FOR USE IN TREATMENT AND PREVENTION OF BACTERIAL INFECTION ADVANCED MEDICINE, INC. 2002-05-21 US disclosed
US-20020022590-A1 Useful as antibiotics; reduced tissue accumulation and/or nephrotoxicity when administered to a mammal; useful against vancomycin-resistant microorganisms CUMBERLAND PHARMACEUTICALS INC. 2002-02-21 US disclosed
WO-2001098328-A2 GLYCOPEPTIDE PHOSPHONATE DERIVATIVES THERAVANCE, INC. (US) 2001-12-27 WO disclosed
EP-1140993-A1 GLYCOPEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME Advanced Medicine, Inc. (US) 2001-10-10 EP disclosed
WO-2001057071-A2 GLYCOPEPTIDE DERIVATIVES HAVING ANTIBIOTIC ACTIVITY ADVANCED MEDICINE, INC. (US) 2001-08-09 WO disclosed
WO-2000039156-A1 GLYCOPEPTIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME ADVANCED MEDICINE, INC. (US) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036219-B2 Methods of treating infections in overweight and obese patients using antibiotics NCEH1, NRDC, LPL KMT2A 3253/4885FABP5 601/4885FABP7 1587/4885
US-20240165100-A1 METHODS OF TREATING INFECTIONS IN OVERWEIGHT AND OBESE PATIENTS USING ANTIBIOTICS CLPP, MGAM, MMP8 KMT2A 3154/4885FABP5 458/4885FABP7 1808/4885
US-20020022590-A1 Useful as antibiotics; reduced tissue accumulation and/or nephrotoxicity when administered to a mammal; useful against vancomycin-resistant microorganisms GLS, PIGS, PAG1 KMT2A 4773/4885FABP5 1107/4885FABP7 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.