Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | GHSR | Q92847 | 2/20 | 0.46 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.44 |
| ▸ | FNTB | P49356 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30764707 | 0.84 | HSD11B1 (0.55) | KDM4EALDH1A1HSD11B1GFERATM | |
| SCHEMBL30764717 | 0.82 | HSD11B1 (0.46) | KDM4EALDH1A1HSD11B1GHSRGFER | |
| SCHEMBL30764713 | 0.81 | HSD11B1 (0.47) | KDM4EALDH1A1HSD11B1GHSRNPC1 | |
| SCHEMBL30764715 | 0.80 | HSD11B1 (0.51) | HSD11B1GHSRGFERATMCHRM2 | |
| SCHEMBL30764763 | 0.78 | HSD11B1 (0.46) | HSD11B1GHSRSMN1; SMN2CHRM2KMT2A | |
| SCHEMBL30764702 | 0.75 | GHSR (0.46) | ALDH1A1HSD11B1GHSRCHRM2KMT2A | |
| SCHEMBL30764735 | 0.75 | HSD11B1 (0.51) | ALDH1A1HSD11B1GFERATMKMT2A | |
| SCHEMBL30764749 | 0.74 | HSD11B1 (0.49) | HSD11B1GFERATMKMT2AMEN1 | |
| SCHEMBL30764755 | 0.74 | GAA (0.54) | KDM4EALDH1A1HSD11B1NPC1RAB9A | |
| SCHEMBL30764757 | 0.73 | HSD11B1 (0.46) | ALDH1A1HSD11B1GHSRGFERATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568968-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | Remynd N.V. (BE) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033479-A1 | (AZA)SPIROHEPTANE DERIVATIVES FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS | REMYND N.V. (BE) | 2024-02-15 | — | — | WO | disclosed |