Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20986010 | 1.00 | AR (0.52) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL26621625 | 0.86 | AR (0.52) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL26621473 | 0.86 | AR (0.52) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL31735481 | 0.86 | AR (0.50) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL18491500 | 0.86 | AR (0.49) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL2420811 | 0.81 | CYP1A2 (0.53) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL12475322 | 0.81 | PLG (0.51) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL9541765 | 0.81 | HTR7 (0.46) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL30764997 | 0.80 | PLG (0.48) | ARKRASPLGPLAUSLC6A2 | |
| SCHEMBL5591112 | 0.80 | KRAS (0.52) | ARKRASPLGPLAUSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568971-A1 | ANTAGONISTS OF 5-HYDROXYTRYPTAMINE RECEPTOR SUBTYPE 2B | Vanderbilt University (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024036183-A1 | ANTAGONISTS OF 5-HYDROXYTRYPTAMINE RECEPTOR SUBTYPE 2B | VANDERBILT UNIVERSITY (US) | 2024-02-15 | — | — | WO | disclosed |