Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | BCR | P11274 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LIPC | P11150 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27262537 | 1.00 | ABL1 (0.35) | ABL1BCRHPGDSLC6A7FASN | |
| SCHEMBL30765184 | 0.91 | CCNC (0.35) | ABL1BCRSLC6A7LIPCCCNT1 | |
| SCHEMBL27262365 | 0.89 | TGFBR1 (0.42) | HPGDCCNT1CDK9KCNH2RAF1 | |
| SCHEMBL30765407 | 0.89 | TGFBR1 (0.42) | HPGDCCNT1CDK9KCNH2RAF1 | |
| SCHEMBL27262456 | 0.85 | NAMPT (0.37) | ABL1BCRHPGDNAMPT | |
| SCHEMBL30765341 | 0.85 | NAMPT (0.37) | ABL1BCRHPGDNAMPT | |
| SCHEMBL30765360 | 0.84 | PIK3C3 (0.34) | NAMPTCCNT1CDK9GABRA5RAF1 | |
| SCHEMBL27262867 | 0.84 | KDM5A (0.39) | SLC6A7 | |
| SCHEMBL30765178 | 0.83 | NPC1 (0.43) | HPGDNAMPTSMN1; SMN2HSD17B10 | |
| SCHEMBL30765379 | 0.83 | NPC1 (0.43) | HPGDNAMPTSMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |