Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 6/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CYP8B1 | Q9UNU6 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765514 | 0.80 | ALDH1A1 (0.48) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765505 | 0.77 | GAA (0.34) | HDAC6P2RY12GAAL3MBTL1MEN1 | |
| SCHEMBL30766019 | 0.76 | LMNA (0.54) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765839 | 0.69 | MEN1 (0.49) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765661 | 0.69 | MEN1 (0.48) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765447 | 0.67 | L3MBTL1 (0.65) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30766020 | 0.67 | MEN1 (0.46) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765740 | 0.66 | MEN1 (0.45) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765592 | 0.65 | L3MBTL1 (0.50) | LMNATSHRMAPK1NPSR1ALDH1A1 | |
| SCHEMBL30765500 | 0.62 | ALDH1A1 (0.41) | ALDH1A1KDM4ESMN1; SMN2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |