Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24750258 | 1.00 | NR4A1 (0.45) | NR4A1SCN5ASCN9AKCNH2SOS1 | |
| SCHEMBL30459994 | 0.89 | GPR3 (0.46) | SCN5ASCN9AKIF11GPR3GAA | |
| SCHEMBL1275899 | 0.89 | GPR3 (0.46) | SCN5ASCN9AKIF11GPR3GAA | |
| SCHEMBL23651402 | 0.85 | NR4A1 (0.65) | NR4A1SCN5ASCN9AKCNH2GPR3 | |
| SCHEMBL11019127 | 0.84 | NR4A1 (0.61) | NR4A1SOS1GAASMN1; SMN2LMNA | |
| SCHEMBL24751459 | 0.82 | L3MBTL1 (0.47) | NR4A1SCN5ASCN9AKCNH2SOS1 | |
| SCHEMBL24750157 | 0.81 | NR4A1 (0.44) | NR4A1SCN5ASCN9AKCNH2SOS1 | |
| SCHEMBL31694862 | 0.81 | NR4A1 (0.44) | NR4A1SCN5ASCN9AKCNH2SOS1 | |
| SCHEMBL17064421 | 0.79 | MAOA (0.54) | NR4A1SOS1GAASMN1; SMN2NPC1 | |
| SCHEMBL29525311 | 0.79 | MAOA (0.54) | NR4A1SOS1GAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500786-A | TEAD inhibitors | 奥赖恩公司 | 2024-02-02 | — | — | CN | disclosed |