Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1275899 | 1.00 | GPR3 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL24750258 | 0.89 | NR4A1 (0.45) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL30768354 | 0.89 | NR4A1 (0.45) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL519232 | 0.83 | ALDH1A1 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL29546263 | 0.83 | NR4A1 (0.56) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL442684 | 0.83 | NR4A1 (0.56) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL10582819 | 0.82 | CETP (0.37) | GPR3SCN9AHSD17B10ALOX5APFEN1 | |
| SCHEMBL30695891 | 0.82 | KIF11 (0.39) | GPR3NPC1RAB9ALMNATP53 | |
| Hydrochloric Acid SCHEMBL9526864 | 0.81 | NR4A1 (0.54) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL10586066 | 0.78 | LMNA (0.41) | GPR3LMNAHSD17B10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12410159-B2 | Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors | MERCK SHARP & DOHME LLC (US) | 2025-09-09 | — | — | US | disclosed |
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2025-07-01 | — | — | US | disclosed |
| EP-4554935-A1 | METHODS OF PREPARING AN ISOINDOLINONE DERIVATIVE AND CRYSTAL FORMS THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-05-21 | — | — | EP | disclosed |
| CN-119630648-A | Process for the preparation of isoindolinone derivatives and crystalline forms thereof | 蒙特罗莎治疗股份有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-118852145-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |
| CN-118184639-A | GSPT1 degradation agent and application thereof | 南京圣和药业股份有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117720550-A | Synthesis method of (S) -3-methyl-4-oxo-2-oxa-8-azaspiro [4.5] decane-8-carboxylic acid tert-butyl ester | 深圳市华先医药科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024015565-A1 | METHODS OF PREPARING AN ISOINDOLINONE DERIVATIVE AND CRYSTAL FORMS THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| CN-117242060-A | Isoindolinone compounds | 蒙特罗萨医疗公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-116457346-A | Preparation of indolone derivatives as novel diacylglycerol O-acyltransferase 2 inhibitors | 默沙东有限责任公司 | 2023-07-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12410159-B2 | Preparation of oxindole derivatives as novel diacylglyceride O-acyltransferase 2 inhibitors | DGAT2, DGAT1, MOGAT2 | GPR3 1356/4885NPC1 159/4885RAB9A 3183/4885 |
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | NOS1, NOS3, NOS2 | GPR3 3747/4885NPC1 1196/4885RAB9A 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.