Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30459994 | 1.00 | GPR3 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL24750258 | 0.89 | NR4A1 (0.45) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL30768354 | 0.89 | NR4A1 (0.45) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL519232 | 0.83 | ALDH1A1 (0.46) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL29546263 | 0.83 | NR4A1 (0.56) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL442684 | 0.83 | NR4A1 (0.56) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL10582819 | 0.82 | CETP (0.37) | GPR3SCN9AHSD17B10ALOX5APFEN1 | |
| SCHEMBL30695891 | 0.82 | KIF11 (0.39) | GPR3NPC1RAB9ALMNATP53 | |
| Hydrochloric Acid SCHEMBL9526864 | 0.81 | NR4A1 (0.54) | GPR3NPC1RAB9AGMNNUSP2 | |
| SCHEMBL10586066 | 0.78 | LMNA (0.41) | GPR3LMNAHSD17B10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2025-07-01 | — | — | US | claimed |
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | claimed |
| US-12428411-B2 | Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors | MERCK SHARP & DOHME LLC (US) | 2025-09-30 | — | — | US | disclosed |
| US-12391663-B2 | Isoindolinone compounds | MONTE ROSA THERAPEUTICS AG (CH) | 2025-08-19 | — | — | US | disclosed |
| EP-4554935-A1 | METHODS OF PREPARING AN ISOINDOLINONE DERIVATIVE AND CRYSTAL FORMS THEREOF | Monte Rosa Therapeutics AG (CH) | 2025-05-21 | — | — | EP | disclosed |
| WO-2025054339-A1 | TRIAZOLOPYRIDINE COMPOUNDS AS INHIBITORS OF KIT | ARCUS BIOSCIENCES, INC. (US) | 2025-03-13 | — | — | WO | disclosed |
| WO-2025026218-A1 | ARYLAMINE COMPOUND HAVING PROTEIN DEGRADATION EFFECT | 杭州中美华东制药有限公司 | 2025-02-06 | — | — | WO | disclosed |
| WO-2025016457-A1 | NEW SUBSTITUTED HETEROCYCLIC COMPOUND AS GSPTS/MYC SIGNAL FLUX REGULATOR | 杭州德睿智药科技有限公司 | 2025-01-23 | — | — | WO | disclosed |
| WO-2024222614-A1 | HETEROCYCLIC GSPT1 DEGRADATION AGENT | 北京诺诚健华医药科技有限公司 | 2024-10-31 | — | — | WO | disclosed |
| US-20240327391-A1 | PREPARATION OF OXINDOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-10-03 | — | — | US | disclosed |
| US-20240294495-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS AG (CH) | 2024-09-05 | — | — | US | disclosed |
| US-20040214817-A1 | Diaminotriazoles useful as inhibitors of protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2004-10-28 | — | — | US | disclosed |
| WO-2004046120-A2 | DIAMINOTRIAZOLES USEFUL AS INHIBITORS OF PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-06-03 | — | — | WO | disclosed |
| WO-2000011954-A1 | HERBICIDAL METHOD | AVENTIS CROPSCIENCE S.A. (FR) | 2000-03-09 | — | — | WO | disclosed |
| EP-0315862-B1 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1994-04-13 | — | — | EP | disclosed |
| EP-0318704-B1 | 3-CYANO-4-PHENYL-PYRROLE DERIVATIVES | BAYER AG (DE) | 1992-12-02 | — | — | EP | disclosed |
| US-5015757-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-4960789-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1990-10-02 | — | — | US | disclosed |
| EP-0318704-A2 | 3-Cyano-4-phenyl-pyrrole derivatives | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |
| EP-0315862-A2 | Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation | BAYER AG (DE) | 1989-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240327391-A1 | PREPARATION OF OXINDOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE O-ACYLTRANSFERASE 2 INHIBITORS | DGAT2, DGAT1, MOGAT2 | GPR3 1356/4885NPC1 159/4885RAB9A 3183/4885 |
| US-12391663-B2 | Isoindolinone compounds | CYP4F2, AOC2, AOC3 | GPR3 957/4885NPC1 285/4885RAB9A 3175/4885 |
| US-20240294495-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | CRBN, GSPT1, GSPT2 | GPR3 1739/4885NPC1 2483/4885RAB9A 2344/4885 |
| US-12428411-B2 | Preparation of oxindole derivatives as novel diacylglyceride o-acyltransferase 2 inhibitors | DGAT2, DGAT1, MOGAT2 | GPR3 1356/4885NPC1 159/4885RAB9A 3183/4885 |
| US-20040214817-A1 | Diaminotriazoles useful as inhibitors of protein kinases | MAP3K20, MAP3K1, MAP3K5 | GPR3 1852/4885NPC1 2770/4885RAB9A 3309/4885 |
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | NOS1, NOS3, NOS2 | GPR3 3747/4885NPC1 1196/4885RAB9A 2192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.