Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769418 | 0.89 | PTGES (0.47) | FFAR1NR4A2MAOBPTGESPOLB | |
| SCHEMBL30768907 | 0.74 | MAOB (0.41) | MAOBPTGESSMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4883970 | 0.74 | NR1H4 (0.53) | SPHK1KMT2ASPHK2 | |
| Carbamic Acid SCHEMBL5490536 | 0.72 | ALDH1A1 (0.59) | FFAR1SPHK1SMN1; SMN2KMT2ASPHK2 | |
| SCHEMBL5880829 | 0.72 | FFAR1 (0.57) | FFAR1NR4A2MAOBCYP4F2CYP4A11 | |
| SCHEMBL8411917 | 0.71 | POLB (0.62) | NR4A2MAOBPOLBPTPN1SPHK1 | |
| SCHEMBL15761340 | 0.71 | BCHE (0.70) | FFAR1NR4A2MAOBCYP4F2CYP4A11 | |
| SCHEMBL8190935 | 0.71 | NR4A2 (0.60) | NR4A2MAOBPTPN1KMT2ASPHK2 | |
| SCHEMBL1635888 | 0.70 | FOXM1 (0.58) | CYP4F2CYP4A11SPHK1SMN1; SMN2KMT2A | |
| SCHEMBL10110920 | 0.70 | METAP2 (0.47) | SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |