Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7449956 | 0.87 | SMN1; SMN2 (0.49) | POLBKDM4EALDH1A1LMNAL3MBTL1 | |
| SCHEMBL30769298 | 0.86 | MAOB (0.52) | PTGESBCHEKDM4EALDH1A1MAOB | |
| SCHEMBL6384064 | 0.82 | MRGPRX4 (0.49) | POLBKDM4EALDH1A1LMNAHTT | |
| SCHEMBL7807431 | 0.80 | ALOX5 (0.55) | KDM4EMAOBADAM17 | |
| SCHEMBL6440684 | 0.77 | ALOX5 (0.56) | KDM4EMAOBADAM17NR4A2 | |
| SCHEMBL6172920 | 0.76 | KMT2A (0.50) | POLBALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL24901890 | 0.74 | ADAM17 (0.49) | BCHEPOLBLMNAMAOBADAM17 | |
| SCHEMBL1008116 | 0.73 | LTB4R (0.61) | BCHEKDM4EALDH1A1LMNAMAOB | |
| SCHEMBL7810873 | 0.72 | ALOX5 (0.67) | KDM4EALDH1A1LMNAADAM17 | |
| SCHEMBL7708009 | 0.72 | CYP4F2 (0.53) | PTGESBCHEPOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |