SCHEMBL30769876

SCHEMBL30769876

Nc1nccc(C2CCN(C=O)CC2)c1N

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IKBKE Q14164 1/20 0.34
TBK1 Q9UHD2 1/20 0.34
NOS3 P29474 1/20 0.33
NOS2 P35228 1/20 0.33
CYP17A1 P05093 6/20 0.32
MTOR P42345 1/20 0.31
DHFR P00374 1/20 0.31
HSP90AA1 P07900 2/20 0.31
HSP90AB1 P08238 2/20 0.31
NEK2 P51955 1/20 0.31
RBP4 P02753 1/20 0.30
HTR1D P28221 1/20 0.30
HTR1B P28222 1/20 0.30
HTR1F P30939 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29526095 0.80 NOS3 (0.45) NOS3NOS2CYP17A1
SCHEMBL928999 0.80 NOS3 (0.45) NOS3NOS2CYP17A1
SCHEMBL15972446 0.78 NEK2 (0.38) NEK2RBP4
SCHEMBL5776718 0.75 TDO2 (0.42) NOS3NOS2CYP17A1
SCHEMBL5776461 0.75 TDO2 (0.42) NOS3NOS2CYP17A1
SCHEMBL5775480 0.75 TDO2 (0.42) NOS3NOS2CYP17A1
SCHEMBL551586 0.75 SLC18A3 (0.46)
SCHEMBL27060040 0.74 IKBKE (0.32) IKBKETBK1
SCHEMBL7846227 0.72 NOS2 (0.51) NOS3NOS2
SCHEMBL23368535 0.72 RBP4 (0.38) IKBKETBK1RBP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI-AVENTIS RECHERCHE & DÉVELOPPEMENT (FR) 2026-01-22 US disclosed
EP-4558500-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF Sanofi (FR) 2025-05-28 EP disclosed
WO-2024017977-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF SANOFI (FR) 2024-01-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022116-A1 IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF MAPK1, MAPK3, MAPK6 IKBKE 950/4885TBK1 3139/4885NOS3 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.