SCHEMBL30775122

SCHEMBL30775122

Clc1cccc(C2(c3ccccc3)N=CC=CN2)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.35
BACE1 P56817 1/20 0.35
BACE2 Q9Y5Z0 1/20 0.35
SLC6A3 Q01959 5/20 0.32
SLC6A4 P31645 4/20 0.32
SCN2A Q99250 1/20 0.31
IDO1 P14902 1/20 0.31
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29135039 1.00 CTSD (0.35) CTSDBACE1BACE2SLC6A3SLC6A4
SCHEMBL23277168 0.70 PGR (0.38) BACE1SCN2AIDO1NPC1RAB9A
SCHEMBL4853361 0.68
SCHEMBL10747995 0.65
SCHEMBL12472612 0.61 ALDH1A1 (0.36) CTSDBACE1BACE2SLC6A3SLC6A4
Chlorobenzene SCHEMBL11493758 0.58 TSHR (0.73) NPC1RAB9AMEN1LMNAMAPT
SCHEMBL8195018 0.58 SLC6A3 (0.44) SLC6A3SLC6A4TSHRSLC6A2CHRNA1
SCHEMBL24156030 0.57 MEN1 (0.48) CTSDBACE1BACE2SLC6A3SLC6A4
1,4-Dichlorobenzene SCHEMBL28152823 0.57 TSHR (0.69) NPC1RAB9AMEN1LMNAMAPT
SCHEMBL3957889 0.56 ESR1 (0.47) SLC6A3SLC6A4MEN1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117343102-A Compound, organic electroluminescent device and display device SK株式会社 2024-01-05 CN disclosed