⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10747995 | 0.73 | — | — | |
| SCHEMBL10763454 | 0.73 | MAOA (0.33) | — | |
| Hydrochloric Acid SCHEMBL12813471 | 0.70 | BACE1 (0.36) | — | |
| SCHEMBL5031169 | 0.69 | KDM4E (0.33) | — | |
| SCHEMBL29135045 | 0.69 | MMP2 (0.32) | — | |
| SCHEMBL30775122 | 0.68 | CTSD (0.35) | — | |
| SCHEMBL29135039 | 0.68 | CTSD (0.35) | — | |
| SCHEMBL5712551 | 0.68 | LMNA (0.33) | — | |
| SCHEMBL23567117 | 0.66 | KMT2A (0.32) | — | |
| SCHEMBL20210762 | 0.66 | NPY5R (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249117-A1 | METHODS FOR STIMULATING OR INDUCING THE GROWTH AND/OR REDUCING THE LOSS OF KERATINOUS FIBERS | SOCIETE LOREAL S.A. (FR) | 2008-10-09 | — | — | US | disclosed |
| US-20080206320-A1 | COMPOSITION COMPRISING AT LEAST ONE 15-PGDH INHIBITOR | SOCIETE L'OREAL S.A. (FR) | 2008-08-28 | — | — | US | disclosed |
| US-7320967-B2 | Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair | L'OREAL (FR) | 2008-01-22 | — | — | US | disclosed |
| EP-1429613-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | Bayer CropScience AG (DE) | 2004-06-23 | — | — | EP | disclosed |
| EP-1418811-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED CYCLIC KETO-ENOLS AND SAFENERS | Bayer CropScience AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1367888-A2 | SELECTIVE SUBSTITUTED ARYL KETONE AND SAFENER BASED HERBICIDES | Bayer CropScience AG (DE) | 2003-12-10 | — | — | EP | disclosed |
| WO-2003026427-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED THIEN-3-YL-SULFONYLAMINO(THIO)CARBONYL-TRIAZOLIN(THI)ONES AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003013249-A1 | SELECTIVE HERBICIDES BASED ON SUBSTITUTED CYCLIC KETO-ENOLS AND SAFENERS | BAYER CROPSCIENCE AG (DE) | 2003-02-20 | — | — | WO | disclosed |
| WO-2002063957-A2 | SELECTIVE SUBSTITUTED ARYL KETONE AND SAFENER BASED HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2002-08-22 | — | — | WO | disclosed |