Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 8/20 | 0.42 |
| ▸ | HTR6 | P50406 | 8/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | HTR3A | P46098 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23064293 | 1.00 | HTR2A (0.48) | HTR2AHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL23074485 | 0.88 | MAPT (0.46) | HTR2AHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL23064319 | 0.86 | SORD (0.50) | HTR2AHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL30778007 | 0.86 | SORD (0.50) | HTR2AHTR1AKDM4EALDH1A1MAPT | |
| SCHEMBL23064393 | 0.84 | HTR7 (0.49) | HTR2AHTR1AHTR7HTR6DRD2 | |
| SCHEMBL30778015 | 0.84 | HTR7 (0.49) | HTR2AHTR1AHTR7HTR6DRD2 | |
| SCHEMBL9035904 | 0.81 | MAT2A (0.48) | HTR2AHTR1AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9037461 | 0.80 | MAT2A (0.47) | HTR2AHTR1AKDM4EALDH1A1CHRNA7 | |
| SCHEMBL1840383 | 0.79 | HRH4 (0.48) | HTR2AHTR1AHTR7HTR6ADRB1 | |
| SCHEMBL13448295 | 0.78 | HTT (0.54) | HTR2AHTR1AKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118678955-A | Pharmaceutical composition for preventing and/or treating heart failure | 国立大学法人大阪大学 | 2024-09-20 | — | — | CN | disclosed |
| CN-112204017-B | Benzisoxazole compounds | 国立大学法人大阪大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-117580577-A | Pharmaceutical composition for preventing and/or treating kidney injury and autophagy activator | 国立大学法人大阪大学 | 2024-02-20 | — | — | CN | disclosed |