SCHEMBL30779705

SCHEMBL30779705

CC(=O)c1cccc(Br)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MEN1 O00255 2/20 0.41
NSD2 O96028 1/20 0.41
POLB P06746 1/20 0.41
MAPT P10636 1/20 0.41
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HPGD P15428 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOB P27338 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
AKR1C4 P17516 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
AKR1C1 Q04828 1/20 0.39
HSPD1 P10809 1/20 0.39
HSPE1 P61604 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1854505 1.00 THRB (0.41) THRBKMT2AKDM4EMEN1NSD2
SCHEMBL7301332 0.84 THRB (0.50) THRBKMT2AKDM4EMEN1NSD2
SCHEMBL438501 0.80 ALDH1A1 (0.57) KMT2AKDM4EALDH1A1HPGDHSD17B10
SCHEMBL30892252 0.80 ALDH1A1 (0.57) KMT2AKDM4EALDH1A1HPGDHSD17B10
SCHEMBL1873518 0.80 KMT2A (0.41) THRBKMT2AKDM4EMEN1ALDH1A1
SCHEMBL166193 0.79 NPC1 (0.52) KMT2AMEN1ALDH1A1HPGDNPC1
SCHEMBL29466485 0.79 NPC1 (0.52) KMT2AMEN1ALDH1A1HPGDNPC1
SCHEMBL6469935 0.78 ALDH1A1 (0.40) KMT2AMEN1ALDH1A1HPGDHSD17B10
SCHEMBL31700607 0.78 ERN1 (0.52) KDM4EMAPTALDH1A1HPGDHSD17B10
SCHEMBL28789921 0.78 ALDH1A1 (0.43) KMT2AKDM4EMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117800956-A Benzo heterocyclic hydrazide hydrazone compound, preparation method and bactericide application 华东理工大学 2024-04-02 CN disclosed