SCHEMBL438501

SCHEMBL438501

O=C(O)c1cccc(Br)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.57
KDM4E B2RXH2 2/20 0.57
HPGD P15428 2/20 0.57
ALB P02768 1/20 0.57
HSD17B10 Q99714 1/20 0.57
MMP2 P08253 1/20 0.57
HNF4A P41235 1/20 0.53
AKR1C4 P17516 2/20 0.53
AKR1C3 P42330 2/20 0.53
AKR1C2 P52895 2/20 0.53
AKR1C1 Q04828 2/20 0.53
PRNP P04156 1/20 0.52
ALOX15 P16050 1/20 0.50
PTPN1 P18031 3/20 0.49
HMGB1 P09429 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30892252 1.00 ALDH1A1 (0.57) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL110532 0.83 ALDH1A1 (0.70) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL28094410 0.80 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDALBHSD17B10
Hydrochloric Acid SCHEMBL28210457 0.80 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDALBHSD17B10
Methane SCHEMBL28154128 0.80 ALDH1A1 (0.67) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL1996333 0.80 ERN1 (0.52) ALDH1A1KDM4EHPGDHSD17B10MMP2
SCHEMBL30779705 0.80 THRB (0.41) ALDH1A1KDM4EHPGDHSD17B10AKR1C4
SCHEMBL31700607 0.80 ERN1 (0.52) ALDH1A1KDM4EHPGDHSD17B10MMP2
SCHEMBL28789921 0.80 ALDH1A1 (0.43) ALDH1A1KDM4EHPGDALBHSD17B10
SCHEMBL1854505 0.80 THRB (0.41) ALDH1A1KDM4EHPGDHSD17B10AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 348 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US claimed
CN-119780057-A Method for synthesizing cannabinoid ADB-4en-PINACA based on benzoxazolyl probe fluorescence detection 中国科学院新疆理化技术研究所 2025-04-08 CN claimed
EP-4501896-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND Kao Corporation (JP) 2025-02-05 EP claimed
CN-118973990-A Process for producing cyclic diketone compound 花王株式会社 2024-11-15 CN claimed
WO-2023189722-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND 花王株式会社 2023-10-05 WO claimed
CN-106518647-A synthesis method of alkyl salicylic acid 中国石油天然气股份有限公司 2017-03-22 CN claimed
CN-102795994-B 5-cyclopropyl-2-hydroxy-benzoic acid, its synthetic method and application method LI HAITAO 2014-12-03 CN claimed
US-4025609-A CHELATION KAO SOAP CO., LTD. (JA) 1977-05-24 US claimed
US-20260069599-A1 INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 AND PHOSPHOINOSITIDE 3-KINASE UNIV NEBRASKA (US) 2026-03-12 US disclosed
US-12497558-B2 Colour change composition and compounds THERMOGRAPHIC MEASUREMENTS LTD (GB) 2025-12-16 US disclosed
US-12435068-B2 Anthelmintic compounds ELANCO ANIMAL HEALTH GMBH (DE) 2025-10-07 US disclosed
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US disclosed
US-20250214920-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND KAO CORPORATION (JP) 2025-07-03 US disclosed
CN-120195932-A Colored resin composition, color filter and display device 住友化学株式会社 2025-06-24 CN disclosed
US-5015721-A Thermotropic liquid-crystalline aromatic, polyesters MONTEDISON S.P.A. (IT) 1991-05-14 US disclosed
WO-1991003200-A1 HYDROXY-ARYL METAL CHELATES FOR DIAGNOSTIC NMR IMAGING THE GENERAL HOSPITAL CORPORATION (US) 1991-03-21 WO disclosed
EP-0394451-A1 MUFFLER NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1990-10-31 EP disclosed
EP-0323710-A1 Thermotropic liquid crystalline aromatic polyesters Montedison S.p.A. (IT) 1989-07-12 EP disclosed
US-4146631-A ANTIALLERGENS, RESPIRATORY DISORDERS MAY & BAKER LIMITED (GB) 1979-03-27 US disclosed
US-4025609-A CHELATION KAO SOAP CO., LTD. (JA) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214920-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND CYP4F2, DUOX1, BCKDK ALDH1A1 973/4885KDM4E 1578/4885HPGD 2243/4885
US-20260069599-A1 INHIBITORS OF BROMODOMAIN-CONTAINING PROTEIN 4 AND PHOSPHOINOSITIDE 3-KINASE BRD4, BRD3, BRPF3 ALDH1A1 4699/4885KDM4E 507/4885HPGD 3576/4885
US-20250214921-A1 METHOD FOR PRODUCING CYCLIC DIKETONE COMPOUND HSD17B7, HSD17B12, BCKDK ALDH1A1 699/4885KDM4E 3153/4885HPGD 441/4885
US-12435068-B2 Anthelmintic compounds H1-10, HRH2, HRH1 ALDH1A1 457/4885KDM4E 3671/4885HPGD 1372/4885
US-12497558-B2 Colour change composition and compounds C5, C9, C3AR1 ALDH1A1 1565/4885KDM4E 1889/4885HPGD 2395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.