Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3528983 | 0.86 | MAPT (0.50) | MAPTCA1CA2CA9ALDH1A1 | |
| SCHEMBL24010110 | 0.82 | KCNH2 (0.47) | MAPTCA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3072168 | 0.75 | MAPT (0.41) | MAPTCA1CA2CA9ALDH1A1 | |
| SCHEMBL24837446 | 0.74 | CA12 (0.63) | MAPTCA1CA2CA9ALDH1A1 | |
| SCHEMBL13589489 | 0.72 | CA12 (0.45) | MAPTCA1CA2CA9ALDH1A1 | |
| SCHEMBL8325233 | 0.71 | PTGDR2 (0.50) | ALDH1A1PKMKDM4EMEN1GAA | |
| SCHEMBL24899728 | 0.71 | CDK1 (0.35) | MAPTCDK1CDK2KDRDRD1 | |
| SCHEMBL23625111 | 0.71 | KDM4E (0.60) | SMN1; SMN2KDM4E | |
| SCHEMBL3086532 | 0.71 | SMN1; SMN2 (0.56) | MAPTALDH1A1PKMSMN1; SMN2LMNA | |
| SCHEMBL21299559 | 0.70 | LOXL2 (0.39) | MAPTCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7829719-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-09 | — | — | US | disclosed |
| US-7829719-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-09 | — | — | US | disclosed |
| US-20100063136-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| EP-1732895-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | Dow Agrosciences LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006060029-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | MAPT 4687/4885CA1 4006/4885CA2 4064/4885 |
| US-20100063136-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | MAPT 4687/4885CA1 4006/4885CA2 4064/4885 |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | MAPT 4687/4885CA1 4006/4885CA2 4064/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | MAPT 4687/4885CA1 4006/4885CA2 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.