SCHEMBL30786128

SCHEMBL30786128

CCNC(=O)c1cccc(F)c1Sc1ccc2c(/C=C/c3cccc(CCN4CCCC4)n3)nn(C3CCCCO3)c2c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30786156 0.92 KDR (0.35) CNR1CNR2
SCHEMBL30786135 0.89 KDR (0.35) CNR1CNR2
SCHEMBL31475216 0.87 DRD2 (0.33)
SCHEMBL30786126 0.86 DRD2 (0.32) CNR1CNR2
SCHEMBL30786218 0.82 KDR (0.31)
SCHEMBL30786176 0.81 KDR (0.45)
SCHEMBL30786231 0.80 DGAT2 (0.35) CNR1CNR2
SCHEMBL30786078 0.79 KDR (0.36) CNR1CNR2
SCHEMBL30786190 0.79 KDR (0.44) CNR1CNR2
SCHEMBL30786153 0.79 KDR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119604488-A Protein tyrosine kinase inhibitor and medical application thereof 苏州必扬医药科技有限公司 2025-03-11 CN disclosed
WO-2024032584-A1 PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF 苏州必扬医药科技有限公司 2024-02-15 WO disclosed