Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786273 | 0.85 | MAPT (0.45) | POLBKDM4EALDH1A1TDP1MYC | |
| SCHEMBL190418 | 0.79 | PKM (0.49) | SLC22A12NSD2POLBSIRT1KDM4E | |
| SCHEMBL7222569 | 0.76 | MYC (0.50) | SLC22A12KDM4EALDH1A1MYC | |
| SCHEMBL12124493 | 0.76 | MAOA (0.59) | SLC22A12NSD2POLBSIRT1KDM4E | |
| SCHEMBL30167732 | 0.74 | MAOA (0.58) | SLC22A12NSD2POLBSIRT1KDM4E | |
| SCHEMBL15638266 | 0.74 | MAOA (0.58) | SLC22A12NSD2POLBSIRT1KDM4E | |
| SCHEMBL8639079 | 0.73 | POLB (0.57) | NSD2POLBSIRT1KDM4EALDH1A1 | |
| SCHEMBL231042 | 0.72 | SIRT1 (0.71) | NSD2POLBSIRT1KDM4EALDH1A1 | |
| SCHEMBL126695 | 0.71 | POLB (0.59) | NSD2POLBKDM4EALDH1A1TDP1 | |
| SCHEMBL5660360 | 0.70 | POLB (0.53) | NSD2POLBSIRT1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |