Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30786209 | 0.85 | SLC22A12 (0.45) | ALDH1A1POLBCYP1A2NPSR1KDR | |
| Hydrochloric Acid SCHEMBL30786175 | 0.77 | MAPT (0.44) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL5887723 | 0.74 | SIRT1 (0.61) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL26676262 | 0.73 | MAPT (0.65) | MAPTALDH1A1HTTPOLBCYP3A4 | |
| SCHEMBL4440485 | 0.73 | HSD17B10 (0.64) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL6934243 | 0.72 | SMN1; SMN2 (0.50) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL4802025 | 0.72 | MAPT (0.55) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL6542706 | 0.71 | KIT (0.56) | ALDH1A1POLBHSD17B10KMT2AGAA | |
| SCHEMBL30786234 | 0.71 | KMT2A (0.43) | MAPTPKLRALDH1A1HTTPOLB | |
| SCHEMBL2224335 | 0.71 | KDM4E (0.55) | MAPTALDH1A1HTTHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| WO-2024032584-A1 | PROTEIN TYROSINE KINASE INHIBITOR AND MEDICAL USE THEREOF | 苏州必扬医药科技有限公司 | 2024-02-15 | — | — | WO | disclosed |