SCHEMBL3079137

SCHEMBL3079137

CC(Cc1ccc(Cl)nc1)CS(C)(=O)=NC#N

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ATM Q13315 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
CHRNA7 P36544 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
AR P10275 1/20 0.34
POLB P06746 1/20 0.33
KDM4E B2RXH2 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL121954 0.81 ALDH1A1 (0.43) ALDH1A1MEN1KMT2AATMCHRNB2
SCHEMBL12797840 0.80 CHRNB2 (0.40) ALDH1A1MEN1KMT2ACHRNB2CHRNA4
SCHEMBL12797900 0.80 SMN1; SMN2 (0.38) ALDH1A1MEN1KMT2ACHRNB2CHRNA4
SCHEMBL12797897 0.79 ALDH1A1 (0.41) ALDH1A1MEN1KMT2AATMCHRNB2
SCHEMBL3079380 0.79 SMN1; SMN2 (0.41) ALDH1A1MEN1KMT2AATMSMN1; SMN2
SCHEMBL6980483 0.77 CHRNB2 (0.36) ALDH1A1MEN1KMT2AATMCHRNB2
SCHEMBL5712087 0.75 SMN1; SMN2 (0.40) ALDH1A1MEN1KMT2ASMN1; SMN2KDM4E
SCHEMBL3073514 0.74 SMN1; SMN2 (0.38) ALDH1A1MEN1KMT2ACHRNB2CHRNA4
SCHEMBL2741813 0.73 MEN1 (0.47) ALDH1A1MEN1KMT2ACHRNB2CHRNA4
SCHEMBL14206918 0.72 AR (0.40) ALDH1A1MEN1KMT2AATMCHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1732895-B1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2016-11-16 EP disclosed
US-7897782-B2 [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides DOW AGROSCIENCES LLC (US) 2011-03-01 US disclosed
US-7897782-B2 [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides DOW AGROSCIENCES LLC (US) 2011-03-01 US disclosed
US-7897782-B2 [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides DOW AGROSCIENCES LLC (US) 2011-03-01 US disclosed
US-7834188-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-16 US disclosed
US-7834188-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-16 US disclosed
US-7834188-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-16 US disclosed
US-7829719-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-09 US disclosed
US-7829719-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-09 US disclosed
US-7829719-B2 Insecticidal N-substituted sulfoximines DOW AGROSCIENCES LLC (US) 2010-11-09 US disclosed
US-20100063136-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-11 US disclosed
US-20100063136-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-11 US disclosed
US-20100063136-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-11 US disclosed
US-20100056578-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056578-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056578-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056579-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056579-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20100056579-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES DOW AGROSCIENCES LLC (US) 2010-03-04 US disclosed
US-20050228027-A1 Insecticidal N-substituted sulfoximines CORTEVA AGRISCIENCE LLC 2005-10-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056579-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES GSS, STS, SMS ALDH1A1 3325/4885MEN1 3396/4885KMT2A 861/4885
US-20100063136-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES GSS, STS, SMS ALDH1A1 3325/4885MEN1 3396/4885KMT2A 861/4885
US-20100056578-A1 INSECTICIDAL N-SUBSTITUTED SULFOXIMINES GSS, STS, SMS ALDH1A1 3325/4885MEN1 3396/4885KMT2A 861/4885
US-20050228027-A1 Insecticidal N-substituted sulfoximines GSS, STS, SMS ALDH1A1 3325/4885MEN1 3396/4885KMT2A 861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.