Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12797840 | 0.81 | CHRNB2 (0.40) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3078810 | 0.80 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3079380 | 0.78 | SMN1; SMN2 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3079137 | 0.74 | ALDH1A1 (0.38) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5712087 | 0.74 | SMN1; SMN2 (0.40) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL18222311 | 0.72 | ALDH1A1 (0.36) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL19976457 | 0.69 | ALDH1A1 (0.44) | ALDH1A1MAPTCHRNB2CHRNA4 | |
| SCHEMBL3078167 | 0.68 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTPOLB | |
| SCHEMBL20361778 | 0.67 | ALDH1A1 (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL770167 | 0.67 | ALDH1A1 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7897782-B2 | [3-(6-Chloropyridin-3-yl)-2-methylpropyl](methyl)oxido- lambda 4-sulfanylidenecyanamide; aphidicides | DOW AGROSCIENCES LLC (US) | 2011-03-01 | — | — | US | disclosed |
| US-7834188-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-16 | — | — | US | disclosed |
| US-7829719-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-11-09 | — | — | US | disclosed |
| US-7795456-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-09-14 | — | — | US | disclosed |
| US-20100076032-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-25 | — | — | US | disclosed |
| US-7678920-B2 | Insecticidal N-substituted sulfoximines | DOW AGROSCIENCES LLC (US) | 2010-03-16 | — | — | US | disclosed |
| US-20100063136-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-11 | — | — | US | disclosed |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2010-03-04 | — | — | US | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056579-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | SMN1; SMN2 253/4885MEN1 3396/4885KMT2A 861/4885 |
| US-20100076032-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | SMN1; SMN2 253/4885MEN1 3396/4885KMT2A 861/4885 |
| US-20100063136-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | SMN1; SMN2 253/4885MEN1 3396/4885KMT2A 861/4885 |
| US-20100056578-A1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | GSS, STS, SMS | SMN1; SMN2 253/4885MEN1 3396/4885KMT2A 861/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | SMN1; SMN2 253/4885MEN1 3396/4885KMT2A 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.