Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 3/20 | 0.47 |
| ▸ | B3GNT2 | Q9NY97 | 4/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30792661 | 0.82 | AURKA (0.49) | AURKAB3GNT2HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL30792672 | 0.76 | B3GNT2 (0.40) | B3GNT2ACACB | |
| SCHEMBL30441384 | 0.70 | AURKA (0.58) | AURKAB3GNT2MEN1KMT2A | |
| SCHEMBL6840348 | 0.69 | KMT2A (0.53) | AURKAB3GNT2HSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL16634710 | 0.66 | DAO (0.54) | AURKAB3GNT2SMN1; SMN2MAPTMEN1 | |
| SCHEMBL20529269 | 0.66 | B3GNT2 (0.64) | AURKAB3GNT2SMN1; SMN2KMT2AHPGD | |
| SCHEMBL1759132 | 0.65 | B3GNT2 (0.61) | AURKAB3GNT2KMT2AHPGD | |
| SCHEMBL16634626 | 0.65 | HSP90AA1 (0.54) | AURKAB3GNT2HSP90AA1SMN1; SMN2CYP3A4 | |
| SCHEMBL15167346 | 0.65 | SPR (0.42) | ACACBSMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL16634724 | 0.64 | TGFBR1 (0.47) | AURKAB3GNT2HSP90AA1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023245137-A1 | SLOW SKELETAL TROPONIN ACTIVATORS | CYTOKINETICS, INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |