SCHEMBL30998151

SCHEMBL30998151

C=CC=CC(=O)NCCC[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 3/20 0.36
ZDHHC2 Q9UIJ5 3/20 0.36
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.30
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL307977 0.84 ZDHHC20 (0.51) ZDHHC20ZDHHC2ALDH1A1KMT2A
SCHEMBL515065 0.83 ZDHHC20 (0.50) ZDHHC20ZDHHC2ALDH1A1KMT2A
SCHEMBL9396182 0.78 ZDHHC20 (0.45) ZDHHC20ZDHHC2ALDH1A1
SCHEMBL9396060 0.78 ZDHHC20 (0.45) ZDHHC20ZDHHC2ALDH1A1
SCHEMBL35590 0.75 ACHE (0.33) ZDHHC20ZDHHC2
SCHEMBL12451661 0.73 KDM4E (0.52) ALDH1A1CYP1A2
SCHEMBL1402612 0.73 KDM4E (0.32) KMT2A
SCHEMBL35366 0.73 ACHE (0.38)
SCHEMBL27994509 0.72 ZDHHC20 (0.43) ZDHHC20ZDHHC2ALDH1A1
SCHEMBL9396161 0.72 ZDHHC20 (0.49) ZDHHC20ZDHHC2ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118235082-A Blue light blocking contact lens and preparation method thereof 晶硕光学股份有限公司 2024-06-21 CN disclosed