Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995342 | 0.85 | CHRNB2 (0.39) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL31286061 | 0.79 | TRPV4 (0.44) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL27033280 | 0.78 | DYRK1A (0.43) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL31286075 | 0.75 | CHRNB2 (0.35) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL32677788 | 0.75 | TRPV4 (0.44) | CHRNB2CHRNA4DYRK1ACTNNB1WNT3A | |
| SCHEMBL30798634 | 0.75 | ALDH1A1 (0.40) | ALDH1A1CTNNB1WNT3A | |
| SCHEMBL7683496 | 0.72 | ESR1 (0.42) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL30798740 | 0.71 | SLC22A12 (0.34) | CHRNB2CHRNA4SLC22A12 | |
| SCHEMBL941915 | 0.71 | CHRNB2 (0.48) | CHRNB2CHRNA4MEN1ALDH1A1GAA | |
| SCHEMBL6119475 | 0.69 | CHRNB2 (0.47) | CHRNB2CHRNA4MEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |