SCHEMBL30799755

SCHEMBL30799755

NC(=O)CC[C@H](NC(=O)[C@@H](N)Cc1ccsc1)C(N)=O

nearest known ligand 0.44

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.44
SLC1A3 P43003 2/20 0.39
SLC1A2 P43004 2/20 0.39
SLC1A1 P43005 2/20 0.39
DPP4 P27487 3/20 0.38
DPP8 Q6V1X1 2/20 0.38
DPP9 Q86TI2 2/20 0.38
CTSS P25774 1/20 0.37
CTSK P43235 1/20 0.37
CTSC P53634 1/20 0.35
MC4R P32245 1/20 0.34
MC3R P41968 1/20 0.34
CTSL P07711 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30799837 0.88 MMP1 (0.43) DPP4DPP8DPP9CTSSCTSC
SCHEMBL30799428 0.83 GHSR (0.52)
SCHEMBL30799746 0.82 CTSC (0.53) MMECTSCMC4RMC3RCTSL
SCHEMBL30799840 0.79 CTSL (0.55) CTSCCTSL
SCHEMBL5257074 0.76 DPP4 (0.48) MMESLC1A3SLC1A2SLC1A1DPP4
SCHEMBL17449974 0.76 DPP4 (0.48) MMESLC1A3SLC1A2SLC1A1DPP4
SCHEMBL30799839 0.76 OPRD1 (0.51) CTSC
SCHEMBL30799945 0.75 CTSL (0.51) MMECTSL
SCHEMBL2242130 0.74 DPP4 (0.57) SLC1A3SLC1A2SLC1A1DPP4DPP8
SCHEMBL2242132 0.74 DPP4 (0.57) SLC1A3SLC1A2SLC1A1DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116985-A1 STAPLED PEPTIDES AND METHODS THEREOF PARABILIS MEDICINES, INC. 2024-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116985-A1 STAPLED PEPTIDES AND METHODS THEREOF CTNNB1, APC, CTNNA1 MME 467/4885SLC1A3 3197/4885SLC1A2 3140/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.