Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPYD | Q12882 | 1/20 | 0.32 |
| ▸ | SOD1 | P00441 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29128325 | 1.00 | LMNA (0.34) | LMNAMAPTPOLBALDH1A1HTT | |
| SCHEMBL30799842 | 0.86 | ALDH1A1 (0.37) | LMNAMAPTPOLBALDH1A1HTT | |
| SCHEMBL29128312 | 0.86 | ALDH1A1 (0.37) | LMNAMAPTPOLBALDH1A1HTT | |
| SCHEMBL29128444 | 0.84 | SOD1 (0.42) | LMNAMAPTPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL30799833 | 0.81 | RAB9A (0.35) | LMNAMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29128456 | 0.81 | RAB9A (0.35) | LMNAMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL29128408 | 0.78 | L3MBTL1 (0.40) | MAPTPOLBSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL29128277 | 0.77 | LMNA (0.38) | LMNAMAPTPOLBALDH1A1HTT | |
| SCHEMBL30800008 | 0.77 | LMNA (0.38) | LMNAMAPTPOLBALDH1A1HTT | |
| SCHEMBL29128168 | 0.75 | POLB (0.32) | LMNAPOLBDPYD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117263862-A | Phenol-1, 3-oxazole/dihydroimidazole-2-ketone/thioketone compound and synthesis and application thereof | 吉首大学 | 2023-12-22 | — | — | CN | disclosed |