Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.35 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21751418 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30800137 | 0.95 | LTB4R (0.40) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL21751395 | 0.95 | LTB4R (0.40) | ALDH1A1KMT2AMEN1RAB9AHTT | |
| SCHEMBL21751381 | 0.95 | MAOA (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30514739 | 0.95 | MAOA (0.38) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL21751333 | 0.92 | MAOA (0.35) | SMN1; SMN2KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL21751347 | 0.91 | MAOA (0.34) | ALDH1A1KMT2AMEN1MAOALTB4R | |
| SCHEMBL21767317 | 0.89 | MAOA (0.36) | SMN1; SMN2KDM4EALDH1A1RAB9AHTT | |
| SCHEMBL21751400 | 0.88 | MAOA (0.35) | SMN1; SMN2ALDH1A1KMT2AMAOAHPGD | |
| SCHEMBL21751314 | 0.88 | ALDH1A1 (0.35) | SMN1; SMN2KDM4EALDH1A1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513188-B | Coelenterazine analogs | 普洛麦格公司 | 2024-01-26 | — | — | CN | disclosed |