Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 8/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801687 | 0.86 | GAA (0.40) | OPRM1OPRL1RIPK1SIRT2SIRT1 | |
| SCHEMBL30801694 | 0.84 | OPRM1 (0.39) | OPRM1OPRL1TACR1RIPK1ALDH1A1 | |
| SCHEMBL19853782 | 0.72 | RIPK1 (0.51) | OPRM1OPRL1RIPK1MEN1KMT2A | |
| SCHEMBL19853779 | 0.70 | GAA (0.51) | OPRM1OPRL1RIPK1ALDH1A1MEN1 | |
| SCHEMBL19839342 | 0.70 | RIPK1 (0.46) | OPRM1OPRL1RIPK1MEN1KMT2A | |
| SCHEMBL19853780 | 0.69 | MEN1 (0.46) | OPRM1OPRL1RIPK1MEN1KMT2A | |
| SCHEMBL15937047 | 0.69 | OPRM1 (0.55) | OPRM1OPRL1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL15937082 | 0.69 | OPRM1 (0.55) | OPRM1OPRL1CYP3A4CYP2D6ALDH1A1 | |
| SCHEMBL30801697 | 0.69 | HDAC1 (0.45) | OPRM1OPRL1RIPK1CYP3A4CYP2D6 | |
| SCHEMBL19839346 | 0.66 | GAA (0.48) | OPRM1OPRL1RIPK1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |