Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 6/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 7/20 | 0.44 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSS | P25774 | 4/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801704 | 0.84 | CCR1 (0.55) | TGM2CCR1CTSLCTSKCTSS | |
| SCHEMBL21987912 | 0.76 | P2RX7 (0.52) | TGM2CCR1ITGB3ITGA2BCTSL | |
| SCHEMBL21987911 | 0.76 | P2RX7 (0.52) | TGM2CCR1ITGB3ITGA2BCTSL | |
| SCHEMBL30101231 | 0.76 | P2RX7 (0.51) | TGM2CCR1CTSLCTSKCTSS | |
| SCHEMBL30801737 | 0.76 | CCR1 (0.48) | CCR1CTSLCTSKCTSSCTSB | |
| SCHEMBL11257246 | 0.74 | TACR1 (0.63) | TGM2CTSLCTSKCTSSCTSB | |
| SCHEMBL11257249 | 0.74 | TACR1 (0.63) | TGM2CTSLCTSKCTSSCTSB | |
| SCHEMBL9819722 | 0.74 | ITGB3 (0.52) | TGM2ITGB3ITGA2B | |
| SCHEMBL10997466 | 0.74 | CTSK (0.54) | TGM2CTSLCTSKCTSSCTSB | |
| SCHEMBL21981478 | 0.74 | CTSK (0.57) | CCR1CTSLCTSKCTSSCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054919-A1 | SPIRO-LACTAM NMDA RECEPTOR MODULATORS AND USES THEREOF | TENACIA BIOTECHNOLOGY (HONG KONG) CO., LIMITED (CN) | 2024-03-14 | — | — | WO | disclosed |