Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYRO3 | Q06418 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 10/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801875 | 0.86 | TYRO3 (0.37) | TYRO3METCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30801838 | 0.86 | OTUD7B (0.35) | CNR1CNR2CYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30801754 | 0.86 | CREBBP (0.35) | TYRO3METCNR2ROCK2 | |
| SCHEMBL23573965 | 0.82 | ROCK2 (0.33) | CNR1CNR2ROCK2 | |
| SCHEMBL30986850 | 0.82 | ROCK2 (0.33) | CNR1CNR2ROCK2 | |
| SCHEMBL23573964 | 0.82 | ROCK2 (0.33) | CNR1CNR2ROCK2 | |
| SCHEMBL30801755 | 0.82 | TYRO3 (0.34) | TYRO3METCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL30801740 | 0.74 | METAP2 (0.33) | CYP2D6SLC6A2SLC6A4SLC6A3ROCK2 | |
| SCHEMBL30801888 | 0.72 | ROCK2 (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3ROCK2 | |
| SCHEMBL30801809 | 0.72 | METAP2 (0.39) | CNR2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |