Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 10/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30802358 | 0.89 | CCR5 (0.48) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 | |
| SCHEMBL30802466 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 | |
| SCHEMBL30802348 | 0.84 | GPR119 (0.49) | SMN1; SMN2NPC1RAB9ACCR5HTT | |
| SCHEMBL20660332 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 | |
| SCHEMBL32691106 | 0.80 | CCR6 (0.46) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 | |
| SCHEMBL30802318 | 0.80 | GPR119 (0.48) | SMN1; SMN2NPC1RAB9ACCR5HTT | |
| SCHEMBL30802304 | 0.80 | GPR119 (0.48) | SMN1; SMN2NPC1RAB9ACCR5HTT | |
| SCHEMBL7134804 | 0.80 | CCR5 (0.51) | SMN1; SMN2NPC1RAB9ACCR5HTT | |
| SCHEMBL7299227 | 0.79 | L3MBTL1 (0.59) | SMN1; SMN2NPC1RAB9ACYP2C19HTR2A | |
| Hydrochloric Acid SCHEMBL20495102 | 0.79 | SMN1; SMN2 (0.58) | SMN1; SMN2NPC1RAB9ACCR5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |