SCHEMBL110765

SCHEMBL110765

NCc1ccc(Br)cc1F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PYCR1 P32322 1/20 0.46
CYP2A6 P11509 1/20 0.44
DGAT1 O75907 1/20 0.44
LOXL2 Q9Y4K0 1/20 0.42
KDM1A O60341 3/20 0.41
KDM1B Q8NB78 1/20 0.41
PDPK1 O15530 1/20 0.40
AKR1B1 P15121 1/20 0.40
TRAP1 Q12931 2/20 0.39
HSP90B1 P14625 1/20 0.39
NAAA Q02083 1/20 0.39
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
HTR2A P28223 2/20 0.38
TAAR1 Q96RJ0 1/20 0.38
TRPM8 Q7Z2W7 1/20 0.38
CHRM5 P08912 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL507122 0.98 PYCR1 (0.45) PYCR1CYP2A6DGAT1LOXL2KDM1A
Hydrochloric Acid SCHEMBL4683452 0.98 PYCR1 (0.45) PYCR1CYP2A6DGAT1LOXL2KDM1A
Hydrochloric Acid SCHEMBL506416 0.96 PYCR1 (0.44) PYCR1CYP2A6DGAT1LOXL2KDM1A
SCHEMBL1819663 0.84 TAAR1 (0.50) PYCR1DGAT1KDM1AKDM1BPDPK1
Hydrochloric Acid SCHEMBL12476650 0.83 TAAR1 (0.48) PYCR1DGAT1KDM1AKDM1BPDPK1
SCHEMBL1106603 0.82 CCR5 (0.45) PYCR1CYP2A6DGAT1LOXL2KDM1A
Hydrochloric Acid SCHEMBL352585 0.80 CCR5 (0.44) PYCR1CYP2A6DGAT1LOXL2KDM1A
SCHEMBL20465750 0.79 PYCR1 (0.47) PYCR1DGAT1KDM1AKDM1BPDPK1
SCHEMBL308050 0.79 PYCR1 (0.47) PYCR1DGAT1KDM1AKDM1BPDPK1
SCHEMBL15806743 0.79 PYCR1 (0.47) PYCR1DGAT1KDM1AKDM1BPDPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114634487-B Preparation method of quinoline feed additive with immunity improving function 河南湾流生物科技有限公司 2024-08-13 CN claimed
CN-114634487-A Preparation method of quinoline feed additive with function of improving immunity 河南湾流生物科技有限公司 2022-06-17 CN claimed
EP-3112340-B1 METHOD FOR PRODUCING 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO, AND PRECURSOR OF 4-BORONO-L-PHENYLALANINE HAVING 18F ATOM INTRODUCED THEREINTO STELLA PHARMA CORP (JP) 2020-07-15 EP claimed
US-9833768-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-12-05 US claimed
US-20170320041-A1 AFFINITY REAGENTS FOR PROTEIN PURIFICATION IMPOSSIBLE FOODS INC. 2017-11-09 US claimed
US-9737875-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-08-22 US claimed
US-9434737-B2 Process for producing optically active succinimide derivatives and intermediates thereof SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2016-09-06 US claimed
US-8900830-B2 Process for producing optically active succinimide derivatives SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-12-02 US claimed
US-20140099681-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF KYOWA HAKKO BIO CO., LTD. (JP) 2014-04-10 US claimed
US-20130196388-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES KYOWA HAKKO BIO CO., LTD. (JP) 2013-08-01 US claimed
US-20120034660-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF KYOWA HAKKO BIO CO., LTD. (JP) 2012-02-09 US claimed
US-20120010405-A1 OPTICALLY ACTIVE 3-AMINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE COMPOUND, AND USE OF THE COMPOUND TANAKA DAISUKE (JP) 2012-01-12 US claimed
US-8030486-B2 Succinic acid diester derivative, process for production thereof, and use of the derivative in the production of pharmaceutical preparation DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-10-04 US claimed
US-20110201807-A1 3-HYDRAZINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE SAME, AND USE OF THE SAME TANAKA DAISUKE 2011-08-18 US claimed
EP-2035375-B1 1,3-DISUBSTITUTED 4-METHYL-1H-PYRROLE-2-CARBOXAMIDES AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS GRUENENTHAL GMBH (DE) 2011-01-19 EP claimed
US-20090286980-A1 OPTICALLY ACTIVE 3-AMINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE COMPOUND, AND USE OF THE COMPOUND DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-11-19 US claimed
US-20090253917-A1 3-HYDRAZINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATES, PROCESS FOR PRODUCTION OF THE SAME, AND USE OF THE SAME DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2009-10-08 US claimed
EP-1212289-A1 PREPARATION OF HALOGENATED PRIMARY AMINES AlliedSignal Inc. (US) 2002-06-12 EP claimed
US-6340773-B1 CATALYTIC HYDROGENATION OF A HALOGENATED OXIME TO FORM HALOGENATED AMINES ALLIEDSIGNAL INC. 2002-01-22 US claimed
WO-2001019779-A1 PREPARATION OF HALOGENATED PRIMARY AMINES ALLIEDSIGNAL INC. (US) 2001-03-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090253917-A1 3-HYDRAZINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATES, PROCESS FOR PRODUCTION OF THE SAME, AND USE OF THE SAME SLC5A1, TERT, CBR3 PYCR1 184/4885CYP2A6 1435/4885DGAT1 263/4885
US-20140099681-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF SDHA, STS, DHPS PYCR1 49/4885CYP2A6 996/4885DGAT1 4447/4885
US-20090286980-A1 OPTICALLY ACTIVE 3-AMINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE COMPOUND, AND USE OF THE COMPOUND REN, GPR119, RANBP1 PYCR1 108/4885CYP2A6 1740/4885DGAT1 143/4885
US-20170320041-A1 AFFINITY REAGENTS FOR PROTEIN PURIFICATION RAB5IF, MRPL21, RPS27A PYCR1 2761/4885CYP2A6 4844/4885DGAT1 3430/4885
US-20120010405-A1 OPTICALLY ACTIVE 3-AMINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE COMPOUND, AND USE OF THE COMPOUND REN, GPR119, RANBP1 PYCR1 108/4885CYP2A6 1740/4885DGAT1 143/4885
US-20120034660-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE SUCCINIMIDE DERIVATIVES AND INTERMEDIATES THEREOF SDHA, STS, ALDH18A1 PYCR1 76/4885CYP2A6 1061/4885DGAT1 4456/4885
US-20110201807-A1 3-HYDRAZINO-2,5-DIOXOPYRROLIDINE-3-CARBOXYLATE, PROCESS FOR PRODUCTION OF THE SAME, AND USE OF THE SAME CBR3, TERT, NOX4 PYCR1 159/4885CYP2A6 1414/4885DGAT1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.