Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30807499 | 1.00 | SIRT1 (0.35) | SIRT1LIMK1KDM4EMAPTKMT2A | |
| SCHEMBL16963100 | 0.85 | PDK1 (0.39) | — | |
| SCHEMBL16616205 | 0.85 | PDK1 (0.39) | — | |
| SCHEMBL16759894 | 0.85 | PDK1 (0.39) | — | |
| SCHEMBL17310817 | 0.73 | CHRNA4 (0.51) | — | |
| Hydrochloric Acid SCHEMBL17310834 | 0.72 | CHRNA4 (0.50) | — | |
| SCHEMBL17112561 | 0.72 | CHRNB2 (0.37) | KMT2A | |
| SCHEMBL7332677 | 0.72 | HTR3A (0.39) | SIRT1LIMK1KDM4E | |
| Hydrochloric Acid SCHEMBL9049059 | 0.71 | HTR3A (0.39) | SIRT1LIMK1 | |
| SCHEMBL17112648 | 0.70 | ATXN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043741-A1 | AUTOTAXIN INHIBITOR COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 주식회사 레고켐 바이오사이언스 | 2024-02-29 | — | — | WO | disclosed |