Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | NAMPT | P43490 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30807828 | 0.86 | RAB9A (0.60) | PKMSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL24077783 | 0.86 | RAB9A (0.60) | PKMSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL7339369 | 0.85 | ALDH1A1 (0.58) | PKMSMN1; SMN2ALDH1A1MAPTRAB9A | |
| SCHEMBL7338663 | 0.83 | TSHR (0.65) | SMN1; SMN2ALDH1A1MAPTRAB9AGAA | |
| SCHEMBL62534 | 0.83 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL27996234 | 0.82 | SMN1; SMN2 (0.73) | SMN1; SMN2ALDH1A1MAPTRAB9AGAA | |
| Hydrochloric Acid SCHEMBL27368126 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AL3MBTL1MEN1 | |
| SCHEMBL62893 | 0.81 | POLB (0.60) | SMN1; SMN2ALDH1A1MAPTRAB9AGAA | |
| SCHEMBL11408485 | 0.80 | KMT2A (0.76) | PKMSMN1; SMN2ALDH1A1MAPTRAB9A | |
| Hydrochloric Acid SCHEMBL133175 | 0.80 | POLB (0.59) | SMN1; SMN2ALDH1A1MAPTRAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622984-A | INHIBITORS OF PHOSPHOLIPASE, VARIOUS PROTEASES | ONO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1997-04-22 | — | — | US | disclosed |
| US-5614555-A | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0588655-B1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5432178-A | Substituted benzoic acid esters; use to prevent or treat inflammatory diseases, allergic diseases, disseminated intravascular coagulation, pancreatitis or multiple organ failure | ONO PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0588655-A1 | Amidinophenol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-03-23 | — | — | EP | disclosed |