Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 9/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.42 |
| ▸ | MTOR | P42345 | 4/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18739747 | 0.81 | PIK3CB (0.49) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL18739552 | 0.81 | PIK3CA (0.53) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL18739258 | 0.80 | PIK3CB (0.55) | PIK3CBPIK3CAPIK3CDPIK3CGMTOR | |
| SCHEMBL30808177 | 0.80 | MET (0.47) | METPIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL18739629 | 0.80 | MET (0.47) | METPIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL30808205 | 0.79 | ALDH1A1 (0.40) | PIK3CAMTORCRHBPCRHR2KMT2A | |
| SCHEMBL30808196 | 0.79 | ALDH1A1 (0.40) | PIK3CAMTORCRHBPCRHR2KMT2A | |
| SCHEMBL30808172 | 0.78 | MET (0.46) | METPIK3CBPIK3CAPIK3CDPIK3CG | |
| SCHEMBL30858052 | 0.77 | SOS1 (0.42) | PIK3CAMTORCRHBPCRHR2KMT2A | |
| SCHEMBL27384805 | 0.77 | SOS1 (0.42) | PIK3CAMTORCRHBPCRHR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026419-A1 | QUINOXALINE DERIVATIVES AS PIK3 ALPHA MODULATORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |