Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.65 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 7/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514888 | 1.00 | GPR119 (0.65) | GPR119TGFBR1NR1H2NR1H3PIK3CA | |
| SCHEMBL5424584 | 0.80 | PKLR (0.56) | GPR119 | |
| SCHEMBL30810384 | 0.80 | GPR119 (0.53) | GPR119TGFBR1NR1H2NR1H3 | |
| SCHEMBL3827483 | 0.79 | PIK3CA (0.66) | GPR119TGFBR1NR1H2NR1H3PIK3CA | |
| SCHEMBL2626628 | 0.78 | GPR119 (0.63) | GPR119TGFBR1NR1H2NR1H3PIK3CA | |
| SCHEMBL30990635 | 0.78 | PIK3CA (0.61) | GPR119TGFBR1NR1H2NR1H3PIK3CA | |
| SCHEMBL7737635 | 0.77 | TGM2 (0.55) | GPR119TGFBR1 | |
| SCHEMBL14696050 | 0.77 | GAA (0.55) | GPR119 | |
| SCHEMBL30198151 | 0.76 | GPR119 (0.60) | GPR119NR1H2PIK3CA | |
| SCHEMBL265132 | 0.76 | GPR119 (0.60) | GPR119NR1H2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543861-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | Nikang Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249970-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |