Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.53 |
| ▸ | F13A1 | P00488 | 5/20 | 0.51 |
| ▸ | TGM2 | P21980 | 5/20 | 0.51 |
| ▸ | TGM1 | P22735 | 5/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.47 |
| ▸ | TGM6 | O95932 | 1/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690890 | 0.94 | F13A1 (0.51) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL29077488 | 0.94 | F13A1 (0.51) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL29640956 | 0.87 | DRD2 (0.49) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL27298866 | 0.87 | DRD2 (0.49) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL24571712 | 0.86 | TMEM97 (0.45) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL30990781 | 0.83 | PKM (0.55) | F13A1TGM2TGM1PKMSMN1; SMN2 | |
| SCHEMBL7870 | 0.81 | L3MBTL1 (0.58) | GPR119PKMSMN1; SMN2HTTTSHR | |
| SCHEMBL26757387 | 0.81 | STS (0.52) | GPR119F13A1TGM2TGM1PKM | |
| SCHEMBL31514888 | 0.80 | GPR119 (0.65) | GPR119NR1H2NR1H3TGFBR1 | |
| SCHEMBL30810488 | 0.80 | GPR119 (0.65) | GPR119NR1H2NR1H3TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543861-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | Nikang Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249970-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING PYRIMIDINE DERIVATIVES FOR DEGRADING CYCLIN-DEPENDENT KINASE 2 VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |