Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15137825 | 0.79 | CA2 (0.43) | HTTSMN1; SMN2POLBCA2LMNA | |
| SCHEMBL16864230 | 0.77 | ALDH1A1 (0.42) | TSHRSMN1; SMN2POLBCA2ALDH1A1 | |
| SCHEMBL8910906 | 0.77 | VCAM1 (0.54) | HTTL3MBTL1SMN1; SMN2POLBVCAM1 | |
| SCHEMBL27345155 | 0.76 | HTT (0.67) | HTTTSHRL3MBTL1SMN1; SMN2VCAM1 | |
| SCHEMBL30811628 | 0.76 | HTT (0.67) | HTTTSHRL3MBTL1SMN1; SMN2VCAM1 | |
| SCHEMBL2474059 | 0.75 | HTT (0.48) | HTTSMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL27344877 | 0.72 | SMN1; SMN2 (0.37) | HTTTSHRSMN1; SMN2POLBVCAM1 | |
| SCHEMBL14433751 | 0.70 | ALDH1A1 (0.47) | HTTTSHRL3MBTL1POLBKDM4E | |
| SCHEMBL15807718 | 0.69 | ALDH1A1 (0.39) | HTTTSHRL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL424432 | 0.67 | ALDH1A1 (0.48) | HTTL3MBTL1SMN1; SMN2POLBVCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543863-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | University Of Ottawa (CA) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023245297-A1 | FERROPTOSIS INHIBITORS AND USES THEREOF | UNIVERSITY OF OTTAWA (CA) | 2023-12-28 | — | — | WO | disclosed |