SCHEMBL30811659

SCHEMBL30811659

C#Cc1cc([N+](=O)[O-])cc2c1c(F)nn2C1CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ CYP4F2 P78329 1/20 0.32
▸ CYP4A11 Q02928 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ RXRA P19793 1/20 0.30
▸ RXRB P28702 1/20 0.30
▸ RXRG P48443 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30811848 0.87 CYP1A2 (0.31) CYP4F2CYP4A11CYP1A2HPGD
SCHEMBL30811764 0.84 CYP4F2 (0.33) CYP4F2CYP4A11CYP1A2HPGD
SCHEMBL30811693 0.80 RXRA (0.37) CYP4F2CYP4A11CYP1A2HPGDRXRA
SCHEMBL2144587 0.75 GAA (0.38) CYP4F2CYP4A11CYP1A2HPGD
SCHEMBL27338781 0.75 MAPT (0.40) CYP4F2CYP4A11CYP1A2HPGD
SCHEMBL2144649 0.73 CYP4F2 (0.35) CYP4F2CYP4A11CYP1A2HPGD
SCHEMBL18260860 0.69 CYP4F2 (0.37) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL31085432 0.69 MAPT (0.38) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL22655613 0.69 MAPT (0.38) CYP4F2CYP4A11RXRARXRBRXRG
SCHEMBL29176199 0.69 RXRA (0.38) CYP4F2CYP4A11CYP1A2HPGDRXRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4582422-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Global Health Drug Discovery Institute (CN) 2025-07-09 — — EP disclosed
US-20250214997-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF GLOBAL HEALTH DRUG DISCOVERY INSTITUTE (CN) 2025-07-03 — — US disclosed
WO-2024056099-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 北京华益健康药物研究中心 2024-03-21 — — WO disclosed
CN-117720533-A MetTL3 inhibitor compound and pharmaceutical composition and application thereof 北京华益健康药物研究中心 2024-03-19 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214997-A1 METTL3 INHIBITOR COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF METTL3, METTL14, METTL16 CYP4F2 235/4885CYP4A11 233/4885CYP1A2 413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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