Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 6/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30814548 | 0.79 | TLR8 (0.44) | TLR8CXCR4AGTR1AGTR2PNP | |
| SCHEMBL4932058 | 0.78 | TLR8 (0.49) | TLR8CXCR4TRPA1AGTR1AGTR2 | |
| SCHEMBL30814463 | 0.71 | AGTR1 (0.35) | AGTR1AGTR2ALDH1A1 | |
| SCHEMBL21393582 | 0.70 | KDM4E (0.49) | ADORA3ADORA2AADORA2BADORA1TRPA1 | |
| SCHEMBL21393588 | 0.68 | ALDH1A1 (0.41) | ADORA3ADORA2AADORA2BADORA1TRPA1 | |
| SCHEMBL21363587 | 0.66 | ALDH1A1 (0.39) | ADORA3ADORA2AADORA2BADORA1TRPA1 | |
| SCHEMBL22477705 | 0.66 | ALDH1A1 (0.39) | ADORA3ADORA2AADORA2BADORA1TRPA1 | |
| SCHEMBL30814682 | 0.66 | CXCR4 (0.81) | TLR8CXCR4POLBHTT | |
| SCHEMBL13217347 | 0.66 | LMNA (0.43) | AGTR1AGTR2DPP4ALDH1A1HPGD | |
| SCHEMBL22477732 | 0.64 | ALDH1A1 (0.38) | ADORA3ADORA2AADORA2BADORA1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024046221-A1 | EGFR INHIBITORS AND USES THEREOF | DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) | 2024-03-07 | — | — | WO | disclosed |