Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817843 | 1.00 | HMOX1 (0.50) | HMOX1ALPGALDH1A1MAPTKMT2A | |
| SCHEMBL6556662 | 0.84 | MAPK1 (0.53) | ALPGALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7792067 | 0.78 | ALPG (0.61) | HMOX1ALPGALDH1A1MAPTKMT2A | |
| SCHEMBL9714015 | 0.76 | LMNA (0.49) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL21821206 | 0.73 | PLAU (0.54) | ALDH1A1KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL30356468 | 0.73 | POLB (0.58) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL1682664 | 0.73 | POLB (0.58) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL30093208 | 0.71 | KCNH2 (0.51) | HMOX1ALPGALDH1A1HSD17B10POLB | |
| SCHEMBL29669830 | 0.70 | CA12 (0.56) | ALPGKDM4E | |
| SCHEMBL10878611 | 0.70 | CA12 (0.56) | ALPGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736157-A | Preparation method of tetrazole-substituted acetophenone compound | 江苏恩华药业股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| US-9434970-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2016-09-06 | — | — | US | disclosed |
| US-20150252398-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-09-10 | — | — | US | disclosed |
| US-9068207-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2015-06-30 | — | — | US | disclosed |
| EP-2445890-B1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-05-06 | — | — | EP | disclosed |
| EP-2488505-B1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-02-25 | — | — | EP | disclosed |
| US-20140073018-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2 Tetrazolyl-Ethyl Ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2014-03-13 | — | — | US | disclosed |
| US-8501436-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2013-08-06 | — | — | US | disclosed |
| US-8404461-B2 | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester | SK Biopharmaceutical Co. Ltd. (KR) | 2013-03-26 | — | — | US | disclosed |
| EP-2488505-A2 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-08-22 | — | — | EP | disclosed |
| EP-2445890-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK Biopharmaceuticals Co., Ltd. (KR) | 2012-05-02 | — | — | EP | disclosed |
| US-20110111467-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| WO-2011046380-A2 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK HOLDINGS CO.,LTD. (KR) | 2011-04-21 | — | — | WO | disclosed |
| WO-2010150946-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK HOLDINGS CO., LTD. (KR) | 2010-12-29 | — | — | WO | disclosed |
| US-20100323410-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | SK BIOPHARMACEUTICALS CO. LTD. (KR) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110111467-A1 | Method for Preparation of Carbamic Acid (R)-1-Aryl-2-Tetrazolyl-Ethyl Ester | CES1, ADH1A, ADH1C | HMOX1 2984/4885ALPG 1722/4885ALDH1A1 46/4885 |
| US-20100323410-A1 | METHOD FOR PREPARATION OF CARBAMIC ACID (R)-1-ARYL-2-TETRAZOLYL-ETHYL ESTER | CPS1, ADH1A, KHK | HMOX1 3993/4885ALPG 2675/4885ALDH1A1 161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.